Faculty of Basic Medical Sciences: Recent submissions
Now showing items 81-100 of 153
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PRODUCTION OF MONOCLONAL AND POLYCLONAL ANTIBODIES FOR THE DIAGNOSIS OF BANANA STREAK VIRUS, GENUS BADNAVIRUS
(2001-07)BSV was isolated and purified from infected leaves of IITA plantain hybrids (TMPx) by Methods A & B. Method A involved the use of sucrose cushion and caesium gradient during ultracentrifugation, while method B involved the ... -
PRESENCE OF N-NITROSAMINES AND RELATED COMPOUNDS IN HUMAN AND ANIMAL FOODS
(1991-02)The nitrosamine, nitrate, ntirite and amine contents of some indigenous vegetables, soup condiments, cereals, food staples and forages of tropical interest were investigated. Also examined were the nitrosation of these ... -
SELECTED GENETIC RED-CELL MARKERS AND THE EPIDEMIOLOGY OF CHLOROQUINE-ASSOCIATED PRURITUS IN NIGERIA
(1994-02)Anecdotal reports suggest that there may be a familial component to Chloroquine-associated pruritus (CAP). To test this hypothesis, the epidemiology of CAP was studied with respect to hemoglobin S (HbS) and glucose-6-phosphate ... -
PHARMACOLOGY STUDIES ON PRAZOSIN, A NEW ANTIHYPERTENSIVE AGENT
(1980-01)The anti-hypertensive drug prazosin brings about a blockage of alpha adrenoceptors which is thought to be different from that caused by conventional alpha adrenoceptor blocking agents. Similarly unlike conventional alpha ... -
DISPOSITION AND ANTIMALARIAL ACTIVITIES OF THE DESETHYL METABOLITES OF CHLOROQUINE
(1985-05)A fluorimetric method for the selective determination of chloroquine (chq) from biological samples following dichloromethane extraction is described. It involves the reaction of the dichloromethane extracted primary and ... -
TOXIC HEMAGGLUTININS IN VARIOUS EDIBLE BEANS AND PEAS
(1974-10)A method involving ammonium sulphate fractionation and dialysis was used in the isolation of phytohemagg-lutininsfrom the young and mature seeds and pods of six edible legumes. The legumes used were soybean (Glycine max—kent ... -
EFFECTS OF TEMPERATURE AND EXERCISE ON THE PRODUCTION AND COMPOSITION OF SWEAT IN NIGERIANS
(1982-12)An investigation into the effects of temperature and exercise on the production and composition of sweat in Nigerians was carried out on healthy male adults. Sweat was induced in a sweat chamber under normal, exercise and ... -
NITROSAMINE CONTAMINATION OF SOME NIGERIAN INDIGENOUS BELIEVES
(1972-12)The possible role of carcinogenic nitrosamines in the aetiology of human cancer has been discussed by experts (O. Basslr, Pers. Comm.; Eisenbrand et al, 1969; Lijinakcy and Epstein, 1970). As a result of this apprehension ... -
THE NUTRIENT COMPOSITION OF SOME NIGERIAN LEAFY GREEN VEGETABLES AND PHYSIOLOGICAL AVAILABILITY OF THEIR IRON CONTENT
(1973-02)ABSTRACT In order to investigate the potential usefulness of local foodstuffs in Nigeria, a comprehensive survey of the various nutrients in 10 local vegetables was carried out. The survey covers: total nitrogen and total ... -
ACTIONS OF SOME ANTIMALARIA AGENTS ON PLAMODIUM BERGHEI BERGHEI AND PLASMODIUM FALCIPARUM IN IN-VIVI AND IN-VITRO MODELS
(1981-07)The antimalarial actions of four drugs,Chloroquine, WR33063, Primaquine and Tetracycline have been studied on P. berqheiberghei in albino Swiss mice and P.falciparum culturein vitro. In the rodent model,the Schizontocidal ... -
CHARACTERIZATION OF NIGERIAN STRAINS OF NEWCASTLE DISEASE VIRUS
(1987-11-27)Natural outbreaks of Newcastle disease were investigated in different parts of Nigeria and samples for virus isolations were collected from vaccinated and unvaccinated commercial farms and indigenous chickens. Eleven NDV ... -
INVESTIGATIONS INTO CHANGES IN PLATELET FUNCTION IN EXPERIMENTAL MALARIA
(1985-08)In this thesis the problem of haemostatic disorders with particular reference to platelet dysfunction in experimental malaria models has been examined. In the Swiss albino mouse model infected with Plasmodium berghei (P. ... -
GROUP B STREPTOCCAL INFECTIONS IN IBADAN
(1983-11)This present study on group B streptococcal (GBS) diseases was carried out between 1977 and 1982 in Ibadan, the largest indigenous Black African city, and capital of Oyo State of Nigeria, with an estimated population of ... -
EFFECTS OF TRIVALENT CHROMIUM ON NORMAL AND INJURED GASTROINTESTINAL TRACT IN LABORATORY RODENTS
(2016-09)Trivalent chromium (Cr3+) is an essential mineral required in quantum with reported health benefits. Chromium deficiency has been linked to symptoms associated with onset of adult diabetes and cardiovascular diseases. ... -
EFFECTS OF CHLOROFORM EXTRACT OF CARICA PAPAYA SEED ON PREGNANCY OUTCOME AND POSTNATAL DEVELOPMENT IN RATS
(2014-01)Increasing frequency of reproductive disorders has been attributed to exposure to harmful exogenous substances during pregnancy. Studies have shown that Carica papaya seed inhibits fertility in male and oestrous cycle ... -
INTESTINAL HAEMODYNAMICS AND GLUCOSE UPTAKE FOLLOWING HEXOSES ADMINISTRATION IN DOGS
(2012-04)An increase in blood glucose levels has been reported to induce a rise in Intestinal Glucose Uptake (IGU) through reduction in Intestinal Vascular Resistance (IVR) and increase in Intestinal Blood Flow (IBF). However, ... -
EFFECTS OF MATERNAL TREATMENT WITH DEXAMETHASONE ON MALE REPRODUCTIVE FUNCTIONS IN THE F1 AND F2 OFFSPRINGS OF WISTAR RATS
(2015-07)Maternal treatment with dexamethasone in threatening preterm delivery leads to high basal corticosterone level. This level may interfere with hormones of hypothalamic-pituitary-gonadal axis in the offspring. However, ... -
EFFECTS OF 1, 4-NAPHTHOQUINONE ON MALE REPRODUCTIVE FUNCTIONS IN MICE
(2014-02)The derivative of naphthoquinone, 1, 4-naphthtoquinone, has been extensively shown to be cytotoxic, with significant antibacterial, antifungal, antiviral, insecticidal, anti-inflammatory and antipyretic properties. Many ... -
MECHANISM OF ANTI-GASTRIC ULCER EFFECT OF BETULINIC ACID IN MALE ALBINO RATS
(2011-03)Betulinic acid (BA) is a lupane-type triterpene that has been identified and isolated from different plant species used in ethnomedicine worldwide. It is known to possess anti-ulcer, anti-tumor and anti-microbial properties. ... -
EFFECTS OF CHLOROQUINE, AMODIAQUINE, SULFADOXINE-PYRIMETHAMINE AND ARTESUNATE ON GASTRIC ACID SECRETION IN RATS
(2011-07)Gastric Acid Secretion (GAS) plays an important role in ulcerogenesis. Some antimalaria drugs have been shown to interfere with gastric mucosal integrity, thereby facilitating the development of gastric ulceration. ...
