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ACTIONS OF SOME ANTIMALARIA AGENTS ON PLAMODIUM BERGHEI BERGHEI AND PLASMODIUM FALCIPARUM IN IN-VIVI AND IN-VITRO MODELS
(1981-07)The antimalarial actions of four drugs,Chloroquine, WR33063, Primaquine and Tetracycline have been studied on P. berqheiberghei in albino Swiss mice and P.falciparum culturein vitro. In the rodent model,the Schizontocidal ... -
AMELIORATIVE ROLE OF SELECTED MICRONUTRIENT SUPPLEMENTS ON OXIDATIVE STRESS AND WOUND HEALING IN DIABETIC RATS AND TYPE 2 DIABETICS
(2012-03)Oxidative Stress (OS) has been implicated in aetiology of Diabetes Mellitus (DM) and its complications including Diabetic Foot Ulcer (DFU). The role of antioxidant micronutrient supplementation on enzymatic and non-enzymatic ... -
ANTIBIOTIC PROPERTIES OF AFFLATOXIN AND SOME OTHER FLOURECENT METABOLITES OF ASPERGILLUS FLAVUS (LINK)
(1971-06)Concentration of constituent of a modius, Ph, and age are known to influence the quality and quantity of metabolites produced by micro-organisms in media. The effects of variation of these parameters on the production of ... -
ANTICANCER, ANTIOXIDANT AND IMMUNO-MODULATORY EFFECTS OF "ACACIA HONEY" IN SOME CANCER CELL LINES
(2014-11)Cancer is one of the leading causes of death worldwide. Cancer curative properties of honey have been documented. However, there is dearth of information on the exact mechanism of anticancer effect of honey. This study was ... -
ANTIGENIC ANALYSIS OF NIGERIAN STRAINS OF WEST NILE VIRUS
(1975-03)Sero-immunological methods were employed to investigate the antigenic relationships among West Nile virus isolates originating in Nigeria. The techniques included neutralization test in new born mice, complement fixation, ... -
ANTIGENOTOXIC ACTIVITIES OF EXTRACTS OF SPONDIAS MOMBIN L.(ANACARDIACEAE) AND CHROMOLAENA ODORATA L. (ASTERACEAE)
(2010-10)Spondias mombin (Anarcadiaceae) and Chromolaena odorata (Asteracea) are common tropical shrubs. Different parts of the plants are used locally as antibacterial, anthelmintic agents and in the treatment of ulcerative wounds ... -
ANTIMALARIAL AND ANTITUBERCULAR ACTIVITIES OF CRUDE METHANOL EXTRACT AND FRACTIONS OF THE BULB OF CRINUM JAGUS ( Linn.)
(2015-02)Crinum jagus is a medicinal plant used traditionally to treat tuberculosis, malaria and other bacterial infections. However, there are limited documented scientific studies to substantiate the use of this plant. Due to ... -
ANTIOXIDANT AND ANTICLASTOGENIC POTENTIALS OF METHANOLIC EXTRACT OF DEFATTED HOLARRHENA FLORIBUNDA LEAVES (G.DON)
(2010-11)Holarrhena floribunda is a widely used plant in herbal formulations against number of disease in Nigeria. There is no sufficient information on the scientific basis for its use. Methanolic leaf extract of defatted H.floribunda ... -
ANTIOXIDANT AND CHEMOPROTECTIVE PROPERTIES OF VERNONIA AMYGALINA DEL. LEAF EXTRACT IN EXPERIMENTAL MODELS OF HEPATOTOXICITY AND HUMAN ERYTHROCYTE LYSIS
(2010)Reactive oxygen species (ROS) have been implicated in the etiology of several pathological and degenerative diseases. Protective effect of natural products possessing antioxidant properties has played very crucial role in ... -
BIOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF METHANOLIC LEAF EXTRACT OF SPONDIAS MOMBIN LINN
(2011)Spondias mombin is used traditionally in Nigeria for the management of malaria, diarrhoea and microbial infections but there is insufficient data from pharmacological investigations on its properties. The effects of the ... -
BIOCHEMICAL STUDIES OF GENETIC VARIANTS OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN NIGERIA
(1969-03)Comparative biochemical studies have been carried out on five genetic variants of human erythrocyte glucose-6-phosphate dehydrogenase in Nigeria. These variants A, A-, B, Ijebu-Ode and Ita-Bale in order of decreasing ... -
BIOCHEMICAL STUDIES OF SOME PLANT EXTRACTS IN USE AS ANTI-MALARIALS IN WESTERN NIGERIA
(1975-09)In order to investigate the antimalarial property of some local medicinal plants namely Asardirachta indica, Morlnda lucida, Alstonia boonei, Enantia ohlorantha and some mixtures of plants used especially in the Western ... -
THE BIOCHEMISTRY AND TECHNOLOGY OF THE PROTEINS OF SOME LEAFY VEGETABLES OF WESTERN NIGERIA
(1971-08)The nutrient composition of six edible leafy vegetables in Nigeria have been determined, and the effect of the age of the plants and of the season of growth on the nutrient levels have also been determined. The crude ... -
A BIOMEDICAL STUDY OF PALMWINE FROM DIFFERENT VARIETIES OF ELAEIS GUINEENSIS
(1966-09)Paper chromatographic analysis of palmwine has shown that it contains sugars, amino acids and organic acids. Six sugars and sugar derivatives identified were fructose, glucose, sucrose, maltose, raffinose, and glueuronic ... -
A BIOMEDICAL STUDY OF THE TRADITIONAL METHOD OF PREPARATION OF 'OGI' AND ITS EFFECTS ON NUTRITIVE VALUE OF CORN
(1966-09)Corn (Zea mays) is an indigenous crop of Africa, widely eaten in the form of sour meal. Amongst the ten million Yorubas in the Western region of Nigeria, it is the traditional staple cereal and the first native food given ... -
CARDIODYNAMIC AND HAEMODYNAMIC ASPECTS OF THE "RELAXATION RESPONSE" IN ADULT NIGERIANS
(1978-09)Experiments were carried out on 120 volunteer, unanaesthetized and intact subjects who were trained to achieve the “Relaxation Response", a behavioral stimulus situation developed as a “transcendent function'' aimed at ... -
CELLULAR IMMUNOLOGY OF PATHOGENIC TRYPANOSOMES
(1970-05)Pathogenic trypanosomes are the cause of a variety of disease syndromes kown collectively as trypanosomiases of man and animals. The association of the tsetse fly (Glossina species) with the transmission of the disease ... -
CEMENT DUST INDUCED-IMMUNOTOXICOLOGICAL AND CELLULAR RESPONSES IN LUNG CELLS
(2013-05)Recent epidemiological studies revealed that exposure to cement dust is associated with development of laryngeal cancer and other metal related diseases. The mechanism of injury to lung cells and disease development by ... -
CHANGES IN THE NUTRITIVE VALUES OF SOME NIGERIAN DIETS AFTER COOKING BY CERTAIN SOUTH EASTERN NIGERIAN TRADITIONAL METHODS
(1972-10)A nutritional study was carried out on six commonly used traditional diets of South-Eastern Nigeria. In this study, the various recipes and the proportion of the foodstuffs used in the formulation of the peasant dietaries ... -
CHARACTERIZATION OF LEUCINE AMINOPEPTIDAE IN TRYPANOSOMA (DUTTONELLA) VIVAX
(1994-09)The genetic diversity in 13 stocks and clones of T. vivax from East and West Africa was compared by isoenzyme analysis of 13 enzymes. The Ugandan and West African stocks and clones showed a very high degree of genetic ...
