The Prevalence of Kidney Dysfunction and Associated Risk Factors among ART-Naïve HIV-1 infected Adults at the University Teaching Hospital in Lusaka, Zambia
View/ Open
Date
2017Author
Tembo, S.
Chirwa, L.
Musonda, P.
Mulenga, L.B.
Mweemba, A.
Type
ArticleLanguage
en_USMetadata
Show full item recordAbstract
This study looks at how chronic HIV infection is associated with renal complications including renal dysfunction. To determine the prevalence of renal dysfunction and associated risk factors in ART naive HIV infected adults in UTH, Lusaka.This was a cross sectional analytic study with 360 participants enrolled. A structured questionnaire was used to collect data. Blood and urine samples were collected for creatinine, CD4 Count, HIV-1 Viroload, serum, hepatitis B surface antigen, hepatitis C antibody, Random blood sugar and urinalysis. Data was entered onto a microsoft office excel spreadsheet, and analysed using STRATA version 13. We investigated the association between the depended variable and each independed variable. The prevalence of renal dysfuction was 24.76%. The overall mean age for the sample population was 36.62 years comprising more females (54.63%) than males. Hypertension OR=2.63, (95%) CI 1.11, 6.12) was the ony factor found to be predictive of renal dysfuction. We recommend routine screening for hypertension in HIV cART naive individuals and those found with hypertension should be furthure investigated for renal dysfunction prior to initiation of cART.
Citation
Tembo, S. Chirwa, L. Musonda, P. Mulenga, L.B. and Mweemba, A. (2017). The Prevalence of Kidney Dysfunction and Associated Risk Factors among ART-Naïve HIV-1 infected Adults at the University Teaching Hospital in Lusaka, Zambia. Medical Journal of Zambia. 44 (3)Sponsorhip
Office of Global AIDS/US Department of State.Publisher
Medical Journal of Zambia
Subject
HIV Infections, Renal dysfunction---ZambiaRenal Insufficiency ---Zambia
HIV Infection, Kidney failure---Zambia
Renal Failure, Antiretroviral therapy---Zambia
Description
Prevalence of renal dysfunction and associated risk factors in ART naive HIV infected adults in UTH
Collections
- Ministry of Health [143]
Related items
Showing items related by title, author, creator and subject.
-
An Infection Prevention Manual For Community And Health Care Institutions In Developing Countries
Chanda, D.O. (University of Zambia, Medical Library, 2004)This Manual on Infection Prevention is based on the principles and policies of Infection Prevention. It is the first Manual to be written on this subject in Zambia. It constitutes years ... -
Antimicrobial susceptibility patterns and their correlate for urinary tract infection pathogens at Kitwe Central Hospital, Zambia.
Chisanga, J.; Mazaba, M.L.; Mufunda, J.; Besa, C.; Kapambwe-muchemwa, M.C.; Siziya, S. (Health Press Zambia Bull., 2017)Inadequate data on antimicrobial susceptibility patterns in the Africa region and indeed in Zambia have led to ineffective empirical treatment before the culture and sensitivity results are made available. The purpose of ... -
The methanol,ethanol and fusel oil contents of some Zambian alcoholic drinks
Conor, R.; Okafor, B.; Nwegbu, M. (Medical Journal of Zambia, 1974)There is considerable evidence that certain Zambian home-produced beers and spirits contain toxic contaminants. Apart from known additives such as methylated spirits and plant juices, high levels of iron, copper and zinc ...