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Never say die: survival signaling in large granular lymphocyte leukemia

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Date
2009
Author
Shah, MV
Zhang, R
Loughran, TP Jr.
Type
Article
Language
en
Metadata
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Abstract
Large granular lymphocyte (LGL) leukemia is a rare disorder of mature cytotoxic T or natural killer cells. Large granular lymphocyte leukemia is characterized by the accumulation of cytotoxic cells in blood and infiltration in the bone marrow, liver, and spleen. Herein, we review clinical features of LGL leukemia. We focus our discussion on known survival signals believed to play a role in the pathogenesis of LGL leukemia and their potential therapeutic implications.
URI
https://library.adhl.africa/handle/123456789/7527
More info.
www.ncbi.nlm.nih.gov/whalecom0/pubmed/19778848
http://hdl.handle.net/11295/30571
Citation
Clin Lymphoma Myeloma. 2009;9 Suppl 3:S244-53.
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