Investigation of suspected Resistance of P. falciparum to Chloroquine in Zambia

Abstract

In 1967 Himpoo and MacCallum (1967) reported three cases of possible chloroquine resistance of P. falciparum in Broken Hill (Kabwe), Zambia. Although a number of such claims of chloroquine resistance in Africa have been published, a report by a World Health Organization Scientific Group (1967) on the Chemotherapy of Malaria stated that such reports are, as yet, unsubstantiated. So far, therefore, there has been no confirmed incidence of a chloroquine resistant strain of P. Faciparum in Africa. For this reason, it was decided to investigate the Suspected chloroquine resistance reported in Kabwe. This investigation has not yet been completed and it will be continued during the main malaria season 1968-1969. The aim of this paper is to present the results of this investigation during the malaria season 1967-.68.