Differential solubility test for haemoglobin S

Abstract

Two hundred and seventy-eight blood specimens were examined, both by the Sickle-quik solubility test and haemoglobin electrophoresis on paper. Two hundred and sixty specimens (96.04%) were correctly identified by the Sicklequik solubility test. Forty-riiiie out of fifty (98%) specimens were interpreted identically when examined independently by two observers.