dc.contributor.author | Mwangombe, Nimrod J M T | |
dc.date.accessioned | 2019-09-04T13:10:31Z | |
dc.date.available | 2019-09-04T13:10:31Z | |
dc.date.issued | 2000 | |
dc.identifier | http://hdl.handle.net/11295/49794 | |
dc.identifier | http://www.ncbi.nlm.nih.gov/pubmed/12862071 | |
dc.identifier.citation | Mwang'ombe N.J, R.B O. 2000. Brain tumours at the Kenyatta National Hospital, Nairobi. East Afr Med J. . 77(8):444-7. | en |
dc.identifier.uri | https://library.adhl.africa/handle/123456789/7396 | |
dc.description.abstract | OBJECTIVE:
To study the frequency, mode of presentation and outcome following treatment of gliomas in patients treated at the Kenyatta National Hospital.
DESIGN:
A retrospective study.
SETTING:
Kenyatta National Hospital, Nairobi, between January 1984 and December 1993.
SUBJECTS:
Two hundred and fourteen patients with intracranial tumours who underwent brain surgery at the Kenyatta National Hospital.
RESULTS:
Two hundred and fourteen histologically confirmed intracranial tumours were seen at the Kenyatta National Hospital between 1984 and 1993. Ninety seven (45.8%) of these were gliomas of which eighty one were astrocytomas, ten ependymomas and six oligodendrogliomas. Meningiomas were the next common tumours (34.4%). Gliomas affected the young age group most, with the peak in the first decade of life. Males were most affected with a male to female ratio of 1.4:1. Features of increased intracranial pressure were the commonest mode of clinical presentation. The parietal region was the commonest site of intracranial gliomas (37.5%). Surgery and radiotherapy were the main forms of definitive/palliative treatment given. The two year survival rate was 25%, for patients who had undergone total tumour excision with or without radiotherapy. Tumour debulking only without post-operative radiotherapy was associated with a seven per cent two year survival rate.
CONCLUSION:
Gliomas were the commonest intracranial tumours (45.8%) seen at the Kenyatta National Hospital over a ten year period (1983-1994). Radical surgery with or without radiotherapy was associated with a 25% two year survival rate, debulking and radiotherapy with 20% two year survival, biopsy and radiotherapy with 20% two year survival and debulking only with a seven per cent two-year survival. Gliomas are less commonly seen in the Kenyan African in comparison with rates of occurrence in the Caucasian race. | |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.title | Brain tumours at the Kenyatta National Hospital, Nairobi | en |
dc.type | Article | en |