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IN VITRO ABSORPTION AND METABOLISM OF SOME NATURAL ESTROGENS IN RAT INTESTINE
(1980-09)In vitro intestinal absorption and metabolism of two natural estrogens, estradiol and estrone sulphate,were studied and compared using uneverted sacs from different segments of the rat intestine. Absorption was measured ... -
THE EFFECT OF COOKING ON THE ASCORBIC ACID CONTENT OF SOME NIGERIAN FOODSTUFFS AND THEIR CONTRIBUTION TO VITAMIN C STATUS OF THE CONSUMERS
(1980-09)In Nigeria, fresh fruits like oranges, guava, mango etc. and leafy vegetables like 'sokoyokoto’ (Celosia argentea L), ' tete ' (Amaranthus spp. L), ‘gbure’ of ascorbic acid (AA.) but these fruits are fast becoming more ... -
CONSUMERS' BEHAVIOUR TOWARDS EXPANDED PROGRAMME OF IMMUNIZATION
(1981)The purpose of this study is to examine the factors that impede the utilisation of the services of the expanded programme of immunization, and make recommendations in the light of the findings as to the strategies for ... -
PROSTAGLANDIN AND GONADOTROPIN STIMULATION OF TESTOSTERONE SECRETION IN THE RAT TESTIS
(1981-01)The response of the rat testis in vitro to gonadotropin and prostagladin El stimulation of testosterone secretion at different stages of rat development was studied. The technique employed involved the incubation of ... -
STUDIES ON THE PROBABLE EFFECT OF PROSTAGLANDINS ON CHOLINERGIC TRANSMISSION IN ISOLATED GUINEA-PIG ILEUM.
(1981-05)The effect of indomethacin, ketoprofen and sodium meclofenamate on contractions evoked by different stimuli in the guinea-pig ileum were investigated in Tyrode solution and in Krebs solution. The whole ileum preparation ... -
STUDIES ON CADMIUM TOXICITY IN RAT TISSUES
(1981-06)The presence of toxic levels of cadmium in the ecosystem has been increasing due to more and more industrial and agricultural use. Though several reports have appeared on renal damage, testicular necrosis and hepatotoxicity, ... -
ACTIONS OF SOME ANTIMALARIA AGENTS ON PLAMODIUM BERGHEI BERGHEI AND PLASMODIUM FALCIPARUM IN IN-VIVI AND IN-VITRO MODELS
(1981-07)The antimalarial actions of four drugs,Chloroquine, WR33063, Primaquine and Tetracycline have been studied on P. berqheiberghei in albino Swiss mice and P.falciparum culturein vitro. In the rodent model,the Schizontocidal ... -
STUDIES OF ZINC AND ALKALINE PHOSPHATE ISOENZYMES IN NORMAL AND TOXAEMIC PREGNANCIES IN NIGERIANS
(1982-03)ABSTRACT There is at present no information on the metabolism of zinc It during pregnancy in Nigerians. A study of zinc and a zinc melalloenzyme was therefore considered worthwhile in normal and toxaemic pregnant Nigerian ... -
UTILISATION OF PRE-SCHOOL CHILDREN'S HEALTH SERVICES IN IBARAPA DISTRICT: IMPLICATION FOR HEALTH EDUCATION
(1982-08)Differential utilisation is a phenomenon common to most health delivery systems. This situation is aggravated when it involves one of the vulnerable groups in the community, who are too young to express their health needs. ... -
POLIOMYELITIS: STUDIES ON DISTRIBUTION OF PARALYSIS AND MANAGEMENT OF DEFORMITIES IN THE LOWER LIMBS OF CHILDREN IBADAN
(1982-09)Poliomyelitis or Heinemedin’s disease is one of the commonest crippling diseases amongst children under the age of five years in Nigeria. Though the disease is found in most parts of the world, it is morenoticeable in ... -
CIRCULATING TUMOUR ASSOCIATED ANTIGENS AS AID TO EARLY DIAGNOSIS OF CARCINOMA OF CERVIX
(1982-10)Earlier studies by this author in 1976 provides evidence of an association between an infective, sexually transmitted agent, the Herpes Simplex Virus Type-2 (HSV-2) and human carcinoma of the cervix, irrespective of ... -
EFFECTS OF TEMPERATURE AND EXERCISE ON THE PRODUCTION AND COMPOSITION OF SWEAT IN NIGERIANS
(1982-12)An investigation into the effects of temperature and exercise on the production and composition of sweat in Nigerians was carried out on healthy male adults. Sweat was induced in a sweat chamber under normal, exercise and ... -
STUDIES IN POSSIBLE BIOCHEMICAL FACTORS IN NIRIDAZONE (Anbilhar) INDUCED TOXICITY
(1983-05)Some biochemical interactions of various doses of Niridazole with tissue components have been studied. In-vivo and in-vitro studies with rats have shown that (14C) Niridazole (Anbilhar) binds covalently to tissue proteins ... -
GROUP B STREPTOCCAL INFECTIONS IN IBADAN
(1983-11)This present study on group B streptococcal (GBS) diseases was carried out between 1977 and 1982 in Ibadan, the largest indigenous Black African city, and capital of Oyo State of Nigeria, with an estimated population of ... -
A COMPARATIVE STUDY OF THE STRUCTURES OF THE RED CELL MEMBRANES AND THE CALCIUM-PUMPING ADENOSINE TRIPHOSPHATASE IN SOME MAMMALIAN SPECIES
(1984-05)Erythrocyte ghost membranes were isolated from blood samples obtained from five mammalian species, namely: (i) human (Homo sapiens), (ii) bovine (Bos taurus), (iii) porcine (Sus scrofa melitensis), (iv) ovine (Ovis aries ... -
A STUDY OF THE EFFECT OF INDUCED MALARIA (P.BERGHEI) ON THE TRANSKETOLAEE ACTIVITY AND RELATED BIOMEDICAL INDICES IN MICE AND RAT
(1984-07)Induced cerebral malaria (P. berghei) studied in mice and rats produced significant loss in the activity of the energy, transketolase which resulted in elevated thiamine pyrophosphate percentage effect (TPP%E) indicating ... -
DIETRY PATTERN AND NUTRITIONAL STATUS OF CHILDREN FROM THE LOW INCOME GROUP OF IBADAN
(1984-08)Nine-hundred and fifteen, 915, mother/children pairs recruited from five clinics In Ibaden were used to study the dietary pattern and nutritional status of infants/children born to poor urban dwellers. Anthropometrlc ... -
A SPECTRUM OF IMMUNITY IN TUBERCULOSIS
(1984-09)ABSTRACT The variable clinical presentation of tuberculosis would suggest a spectrum of host immune responses to the disease. To investigate this hypothesis, 30 hospitalized patients aged 19 to 61 years (moan 34.4 years) ... -
STUDIES ON PROTEIN-ENERGY REQUIREMENTS OF YOUNG ADULT FEMALES IN NIGERIA
(1984-10)A series of studies were carried out to determine the protein and energy requirements of young adult women in Nigeria. The requirements were estimated from nitrogen balance studies while the subjects were fed their habitual ... -
PSYCHO-SOCIAL FEATURES OF IN-PATIENTS IN LONG-STAY PSYCHIATRIC HOSPITALS: CROSS-CULTURAL STUDY
(1985-03)In a survey of 226 patients at the Lantoro annex of Aro Neuropsychiatric Hospital, Abeokute, Nigeria, schizophrenic patients. constituted the largest group 163 (72.1%), followed by organic brain syndrome 37 (16.4%), and ...