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A BIOMEDICAL STUDY OF THE TRADITIONAL METHOD OF PREPARATION OF 'OGI' AND ITS EFFECTS ON NUTRITIVE VALUE OF CORN
(1966-09)Corn (Zea mays) is an indigenous crop of Africa, widely eaten in the form of sour meal. Amongst the ten million Yorubas in the Western region of Nigeria, it is the traditional staple cereal and the first native food given ... -
A BIOMEDICAL STUDY OF PALMWINE FROM DIFFERENT VARIETIES OF ELAEIS GUINEENSIS
(1966-09)Paper chromatographic analysis of palmwine has shown that it contains sugars, amino acids and organic acids. Six sugars and sugar derivatives identified were fructose, glucose, sucrose, maltose, raffinose, and glueuronic ... -
STUDIES ON THE BURKITT AND LYMPHORETICULAR TUMOURS IN NIGERIA
(1966-12)Burkitt’s tumour exemplifies the popular belief that lympho-reticular tumours are relatively more common in African than elsewhere. At the time the present studies were contemplated, its exact histogenesis was controversial, ... -
A STUDY OF THE EFFECT OF THE AFLATOXINS ON BLOOD CLOTTING
(1967-06)The structural configurations of the synthetic coumarins have been shown to be of major importance in their action on blood clotting. In view of the similarities in the structures of the synthetic coumarins and the aflatoxins, ... -
NUTRITIONAL CHANGES IN SOME NIGERIAN FOODS DURING DIETARY PREPARATION AND THEIR EFFECTS ON THE MAMMALIAN BODY
(1967-06)Starting with a comprehensive review of the research already done in the related field of nutrition, the chemical composition of 20 Nigerian food materials which are used in the preparation of six common local diets has ... -
THE EFFECT OF DIET ON THE METABOLISM OF AFLATOXIN IN THE MAMMAL
(1968-04)The metabolic fate of aflatoxin is of interest in connection with studies related to the mode of action of hepatotoxins in the induction of liver tumors. The ability of the toxin to interact with sub-cellular particles and ... -
STUDIES ON TEMPERATURE DISTRIBUTION AND HEAT PRODUCTION IN THE "CORE AREA" OF THE DOG
(1968-06)Temperature distribution within the "oore area" of fasting mongrel dogs was studied with thermocouples or "applicators" (the hot junctions of thermocouples - manufactured by ELLAB Ltd. Copenhagen). The highest intra-abdominal ... -
THE ROLE OF 5-HYDROXYTRYPTAMINE IN THE PATHOGENESIS OF ENDONYOCARDIAL FIBROSIS
(1968-06)ENDONYOCARDIAL FIBROSIS (E.M.F) is a common heart disease in certain areas of Africa. Much knowledge has accumulated in recent years about the pathology and clinical features of this disease; but at present, its pathogenesis ... -
CHEMOTHERAPEUTIC AND IMMUNOLOGICAL STUDIES ON STRAIN OF TRIPANOSOMA CONCOLENSE
(1968-12)(l) The adaptation of two strains of T.congolense from cattle to rats is described. One of them, the Ibadan strain, showed the phenomenon of polymorphism after being transmitted for four and a half years in rats. (2) The ... -
METABOLISM OF LIPIDS IN KWASHIORKOR
(1969)A study of lipid metabolism in Nigeria kwashiorkor children has shown that the serum phospholipids, total cholesterol, cholesterol esters and total fatty acid levels were low when compared with the values for control ... -
BIOCHEMICAL STUDIES OF GENETIC VARIANTS OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN NIGERIA
(1969-03)Comparative biochemical studies have been carried out on five genetic variants of human erythrocyte glucose-6-phosphate dehydrogenase in Nigeria. These variants A, A-, B, Ijebu-Ode and Ita-Bale in order of decreasing ... -
A FUNCTIONAL DIFFERENTIATION OF THE GASTROINTESTINAL TRACT
(1969-04)Needham (1942) in the glossary of his book "Biochemistry and Morphogenesis" defines "functional differentiation" as the differentiation of tissues as the result of forces arising out of the functions which they are ... -
CHEMICAL AND BIOCHEMICAL STUDIES OF TOXIC FLUORESCENT SUBSTANCE PRODUCED BY ASPERGILLUS FLAVUS (LINK) WHEN CULTURED ON PALMSAP
(1969-09)Czapek medium, Czapek-Dox medium, glucose-ammonium nitrate medium and palmwine of different ages have been used in the culture of Aspergillus flavus (Link ex Fries). Of these growth media, unfermented palmwine (palmsap) ... -
CELLULAR IMMUNOLOGY OF PATHOGENIC TRYPANOSOMES
(1970-05)Pathogenic trypanosomes are the cause of a variety of disease syndromes kown collectively as trypanosomiases of man and animals. The association of the tsetse fly (Glossina species) with the transmission of the disease ... -
AN INVESTIGATION OF MECHANISM OF AMPICOGULANT ACTION OF AFLATOXIN IN SOME ANIMAL SPECIES
(1970-06)It has been reported that aflatoxin B₁ isolated from foodstuff contaminated with a toxin strain of Aspergillus Flavus produces in rats a lesion similar to the “sweet clover disease”. Biochemical, Kinetic and microscopic ... -
COBALT AND IRON CONSUMPTION IN MAN ( A COMPARATIVE STUDY OF TH E FACTORS REGULATING ABSORPTION IN SUBJECT WITH OR WITHOUT DISORDERS OF IRON METABOLISM
(1971)A direct correlation was found between the intestinal absorption of cobalt and iron over the range of values where iron absorption is normal or increased. This observation demonstrates that cobalt and iron share at least ... -
SOME IMMUNOLOGICAL REACTIONS OF TRIPANOSONA GAMBIESSE ISOLATES
(1971-02)Serological characteristics and the protective effect of humeral antibodies (serum) were examined in rabbits (a) infected with Trypanosoma gambiense, (b) immunized with killed Trypanosoma gambiense, (c) immunized with ... -
ANTIBIOTIC PROPERTIES OF AFFLATOXIN AND SOME OTHER FLOURECENT METABOLITES OF ASPERGILLUS FLAVUS (LINK)
(1971-06)Concentration of constituent of a modius, Ph, and age are known to influence the quality and quantity of metabolites produced by micro-organisms in media. The effects of variation of these parameters on the production of ... -
THE BIOCHEMISTRY AND TECHNOLOGY OF THE PROTEINS OF SOME LEAFY VEGETABLES OF WESTERN NIGERIA
(1971-08)The nutrient composition of six edible leafy vegetables in Nigeria have been determined, and the effect of the age of the plants and of the season of growth on the nutrient levels have also been determined. The crude ... -
IMMUNOCHEMICAL STUDIES ON THE ANTIGENE OF PLASMODIUM FALCIPARUM MALARIA
(1971-12)ABSTRACT In a previous thesis, the study of certain aspects of the immune response of man to Plasmodium falciparum malaria in Ibadan, Nigeria were investigated. An attempt was made for the search of a suitable source of ...
