Browsing Faculty of Basic Medical Sciences by Title
Now showing items 66-85 of 153
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EVALUATION OF ANTIPSYCHOTIC EFFECTS OF METHYL JASMONATE IN MICE
(2017-01)Psychosis is a chronic neurological disorder that impairs the quality of life of the patients and remains a major health challenge worldwide. Current drugs used to manage psychosis are expensive and only provide symptomatic ... -
EVALUATION OF ANTPSYCHOTIC EFFECTS OF METHYL JASMONATE IN MICE
(2017-01)Psychosis is a chronic neurological disorder that impairs the quality of life of the patients and remains a major health challenge worldwide. Current drugs used to manage psychosis are expensive and only provide symptomatic ... -
EVALUATION OF AUTOANTIBODIES AND HEPATITIS VIRAL MARKERS IN NIGERIANS WITH LIVER DISEASES
(2011-01)Liver disease is a major public health problem. Several diagnostic and aetiologic agents of liver diseases are known, but autoantibodies to liver antigens in Nigerians with liver diseases have not been extensively studied. ... -
EVALUATION OF EPIDEMIOLOGICAL FACTORS OF MEASLES INFECTION AND SEQUENCE ANALYSIS OF A LOCAL ISOLATE OF THE VIRUS IN NIGERIA
(2000-08)Nigerian isolates of measles virus (MVNG) and its nucleotide sequence have not been compared with those of measles virus (MV) isolates from various parts of the world. This study therefore compared the neutralization ... -
EVALUATION OF EXTRACTS OF MORINDA LUCIDA AND OTHER DRUGS FOR ANTIMALARIA ACTIVITY
(1988-09)The impact of the problem of drug resistance on the capacity to provide adequate treatment for malaria is becoming more marked as more countries try to provide treatment facilities for their entire population. The need for ... -
EVALUATION OF MECHANISMS UNDERLYING ANTIDEPRESSANT-LIKE EFFECT OF METHYL JASMONATE IN MICE
(2017-11)Depression is a chronic, recurrent and severe disease that affects millions of individuals worldwide and impairs the quality of life of the patients. The clinical efficacy of existing antidepressants has been compromised ... -
EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITIES OF EXTRACTS AND FLAVONOID-RICH FRACTION FROM Ocimum gratissimum LINN.(LAMIACEAE) LEAF
(2017-08)Inflammatory responses are among causes of ill health, impaired quality of life and untimely death. Naturally occurring phenolics are sale phytochemicals that provides combinatorial multitargeted therapy in chronic ... -
EVALUATION OF THE ANTISPYCHOTIC PROPERTY OF MORIN AND ITS MECHANISMS OF ACTION IN EXPERIMENTAL MICE
(2018-06)Psychosis is a chronic neuropsychiatric disease characterised by severe behavioural perturbations. Current drugs used in the management of the disease are associated with serious side effects. Therefore, compounds with ... -
EXPERIMENTAL STUDIES ON THE ROLE OF NEURO-HUMORAL FACTORS IN PEPTIC ULCERATION
(1977-02)Using as experimental models, chronic and acute peptic ulcerations produced in rats by means of prolonged starvation and indomethacin, the role of (i) the hypothalamo-neurohypophyseal-neuro secretory system (H.N.N.S_) and ... -
A FUNCTIONAL DIFFERENTIATION OF THE GASTROINTESTINAL TRACT
(1969-04)Needham (1942) in the glossary of his book "Biochemistry and Morphogenesis" defines "functional differentiation" as the differentiation of tissues as the result of forces arising out of the functions which they are ... -
GASTRIN CONTENT AND ACTIVITY IN SOME RUMINANTS AND SOME EQUINES
(1973-06)Attempts were made to extract gastrin from the cardiac, fundic pyloric, duedenal osecal and colonic mucosa of goats, sheep, cattle, male and female donkeys, using a modification of the gastrin extraction method introduced ... -
GENETIC DIVERSITY AND CORECEPTOR USAGE OF HIV-1 STRAINS AMONG INFECTED INDIVIDUALS PRESENTING AT A VOLUNTARY COUNSELLING AND TESTING CENTRE IN IBADAN, NIGERIA
(2013)Molecular analyses of Human Immunodeficiency Virus (HIV) have shown great genetic diversity among strains of the virus. The diversity has implications on efficiency of its transmission, pathogenesis, diagnosis, vaccine ... -
GENETICS AND PATHOGENICITY OF THREE H5N1 AVIAN INFLUENZA A VIRUS ISOLATES OF CHICKEN IN SOUTHWESTERN NIGERIA
(2011-09)Highly Pathogenic Avian influenza A (HPAI) H₅NI outbreak has been reported in several African countries including Nigeria. The outbreak continues to pose a risk to human health and livelihood. The genetics and pathogenicity ... -
GROUP B STREPTOCCAL INFECTIONS IN IBADAN
(1983-11)This present study on group B streptococcal (GBS) diseases was carried out between 1977 and 1982 in Ibadan, the largest indigenous Black African city, and capital of Oyo State of Nigeria, with an estimated population of ... -
HISTOCHEMISTRY OF RAT SMALL INTESTINE MUCOSA AFTER ORAL ADMINISTRATION SILVER NITRATE
(1979)The investigations making up the thesis were aimed towards elucidating the structural and histochemical effects of toxic doses of silver nitrate on rat small intestinal mucosa at three different sites. The studies were ... -
HORMONE AND DRUG STIMULATION OF TESTOSTERONE SECRETION IN THE RAT LEYDIG CELL
(1995-07)The steroidogenic response of rat Leydig cell to gonadotrophin and prolactin was used to modify an in vitro experimental model for studies an the effect of some medicinal extracts on testosterone secretion. The crude ... -
HUMAN IMMUNODEFICIENCY VIRUS TYPE-1 SEROTYPES AND SOME ASPECTS OF PHENOTYPIC PROPERTIES OF THE VIRUS ISOLATES IN NIGERIA
(1999-08)Human Immunodeficiency Virus (HIV) is a retrovirus aetiologically and epidemiology associated with the Acquired Immunodeficiency Syndrome (AIDS). The prevalence of HIV infection and the disease and incidence of AIDS are ... -
HUMAN LOIASIS IN WESTERN NIGERIA
(1974-07)An attempt has been made in this study to bridge some of the gaps in our knowledge of loiasis in Western Nigeria. At this same time, areas for future research which might lead to a better understanding of the disease ... -
HYPOLIPIDAEMIC, ANTIOXIDATIVE AND HEPATOPROTECTIVE EFFECTS OF Persea americana (Lauraceae) LEAF EXTRACTS IN RATS)
(2010-05)Hyperlipidaemia and oxidative stress are important factors in the pathogenesis of chronic degenerative and inflammatory diseases. Persea americana (Lauraceae) has been widely used in ethnomedicine in the treatment of various ... -
IMMUNOCHEMICAL STUDIES ON THE ANTIGENE OF PLASMODIUM FALCIPARUM MALARIA
(1971-12)ABSTRACT In a previous thesis, the study of certain aspects of the immune response of man to Plasmodium falciparum malaria in Ibadan, Nigeria were investigated. An attempt was made for the search of a suitable source of ...