Browsing Faculty of Basic Medical Sciences by Title
Now showing items 59-78 of 153
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EFFECTS OF THE LEAF DECOCTION OF MOMORDICA CHARANTIA (BITTER LEMON) ON MITOCHONDRIAL MEMBRANE PERMEABILITY TRANSITION PORE AND FERTILITY IN MALE ALBINO RATS
(2011-06)Certain anti-cancer agents act by inducing the intrinsic pathway of apoptosis which is mediated by the release of cytochrome C when the Mitochrondial Membrane Pemeability Transition (MMPT) pore opens. Several studies have ... -
EFFECTS OF TRIVALENT CHROMIUM ON NORMAL AND INJURED GASTROINTESTINAL TRACT IN LABORATORY RODENTS
(2016-09)Trivalent chromium (Cr3+) is an essential mineral required in quantum with reported health benefits. Chromium deficiency has been linked to symptoms associated with onset of adult diabetes and cardiovascular diseases. ... -
EFFECTS OF VITAMIN C ON CARDIAC AUTONOMIC FUNCTION, OXIDATIVE STRESS AND DYSLIPIDAEMIA IN FRUCTOSE-ALLOXAN DIABETIC RATS
(2017-06)Cardiac Autonomic Neuropathy (CAN) is characterised by cardiac autonomic dysfunction and is the principal cause of mortality in type-2 diabetes. Oxidative stress has been implicated in the aetiology of CAN, thus antioxidants ... -
EFFECTS OF VITAMIN SUPPLEMENT ON PLASMA HOMOCYSTEINE AND APOLIPOPROTEIN A₁ LEVELS IN CHILDREN WITH NEPHROTIC SYNDROME IN IBADAN, NIGERIA
(2013-04)Nephrotic Syndrome (NS), a condition characterized by proteinuria, hypoproteinaemia, and hypercholesterolaemia resulting from damage to the kidneys' glomeruli blood vessel, is a common childhood disease worldwide. Elevated ... -
ENZYME HISTOCHEMISTRY AND FUNCTIONAL DIFFERENTIATION OF THE RAT METANEPHROS
(1973-03)Since histochemistry was introduced into the study of animal tissues, many investigators have localized the site of activity of a number of enzymes in both the developing kidney the adult kidney. Moog (1944) demonstrated ... -
ERECTOGENIC AND SPERMIOLOGIC EFFECTS OF STEM BARK EXTRACTS OF Nauclea Latifolia (Smith) IN RABBITS
(2015-01)Erectile dysfunction is a sexual disorder to which both natural and synthetic remedies are being sought. Extract of Nauclea latifola (NL) has been used in folkloric medicine to ameliorate this sexual disorder; however there ... -
ERYTHROCYTE Ca++, Mg++ ATPase ACTIVITY IN DIABETIC NIGERIANS
(1998-03)CA++, Mg++ -ATPase is an important enzyme in CA++ homeostasis. Its activity has been investigated in conditions like hypertension and sickle cell disease. There is no information in the literature on the activity of CA++, ... -
EVALUATION OF ANTIPSYCHOTIC EFFECTS OF METHYL JASMONATE IN MICE
(2017-01)Psychosis is a chronic neurological disorder that impairs the quality of life of the patients and remains a major health challenge worldwide. Current drugs used to manage psychosis are expensive and only provide symptomatic ... -
EVALUATION OF ANTPSYCHOTIC EFFECTS OF METHYL JASMONATE IN MICE
(2017-01)Psychosis is a chronic neurological disorder that impairs the quality of life of the patients and remains a major health challenge worldwide. Current drugs used to manage psychosis are expensive and only provide symptomatic ... -
EVALUATION OF AUTOANTIBODIES AND HEPATITIS VIRAL MARKERS IN NIGERIANS WITH LIVER DISEASES
(2011-01)Liver disease is a major public health problem. Several diagnostic and aetiologic agents of liver diseases are known, but autoantibodies to liver antigens in Nigerians with liver diseases have not been extensively studied. ... -
EVALUATION OF EPIDEMIOLOGICAL FACTORS OF MEASLES INFECTION AND SEQUENCE ANALYSIS OF A LOCAL ISOLATE OF THE VIRUS IN NIGERIA
(2000-08)Nigerian isolates of measles virus (MVNG) and its nucleotide sequence have not been compared with those of measles virus (MV) isolates from various parts of the world. This study therefore compared the neutralization ... -
EVALUATION OF EXTRACTS OF MORINDA LUCIDA AND OTHER DRUGS FOR ANTIMALARIA ACTIVITY
(1988-09)The impact of the problem of drug resistance on the capacity to provide adequate treatment for malaria is becoming more marked as more countries try to provide treatment facilities for their entire population. The need for ... -
EVALUATION OF MECHANISMS UNDERLYING ANTIDEPRESSANT-LIKE EFFECT OF METHYL JASMONATE IN MICE
(2017-11)Depression is a chronic, recurrent and severe disease that affects millions of individuals worldwide and impairs the quality of life of the patients. The clinical efficacy of existing antidepressants has been compromised ... -
EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITIES OF EXTRACTS AND FLAVONOID-RICH FRACTION FROM Ocimum gratissimum LINN.(LAMIACEAE) LEAF
(2017-08)Inflammatory responses are among causes of ill health, impaired quality of life and untimely death. Naturally occurring phenolics are sale phytochemicals that provides combinatorial multitargeted therapy in chronic ... -
EVALUATION OF THE ANTISPYCHOTIC PROPERTY OF MORIN AND ITS MECHANISMS OF ACTION IN EXPERIMENTAL MICE
(2018-06)Psychosis is a chronic neuropsychiatric disease characterised by severe behavioural perturbations. Current drugs used in the management of the disease are associated with serious side effects. Therefore, compounds with ... -
EXPERIMENTAL STUDIES ON THE ROLE OF NEURO-HUMORAL FACTORS IN PEPTIC ULCERATION
(1977-02)Using as experimental models, chronic and acute peptic ulcerations produced in rats by means of prolonged starvation and indomethacin, the role of (i) the hypothalamo-neurohypophyseal-neuro secretory system (H.N.N.S_) and ... -
A FUNCTIONAL DIFFERENTIATION OF THE GASTROINTESTINAL TRACT
(1969-04)Needham (1942) in the glossary of his book "Biochemistry and Morphogenesis" defines "functional differentiation" as the differentiation of tissues as the result of forces arising out of the functions which they are ... -
GASTRIN CONTENT AND ACTIVITY IN SOME RUMINANTS AND SOME EQUINES
(1973-06)Attempts were made to extract gastrin from the cardiac, fundic pyloric, duedenal osecal and colonic mucosa of goats, sheep, cattle, male and female donkeys, using a modification of the gastrin extraction method introduced ... -
GENETIC DIVERSITY AND CORECEPTOR USAGE OF HIV-1 STRAINS AMONG INFECTED INDIVIDUALS PRESENTING AT A VOLUNTARY COUNSELLING AND TESTING CENTRE IN IBADAN, NIGERIA
(2013)Molecular analyses of Human Immunodeficiency Virus (HIV) have shown great genetic diversity among strains of the virus. The diversity has implications on efficiency of its transmission, pathogenesis, diagnosis, vaccine ... -
GENETICS AND PATHOGENICITY OF THREE H5N1 AVIAN INFLUENZA A VIRUS ISOLATES OF CHICKEN IN SOUTHWESTERN NIGERIA
(2011-09)Highly Pathogenic Avian influenza A (HPAI) H₅NI outbreak has been reported in several African countries including Nigeria. The outbreak continues to pose a risk to human health and livelihood. The genetics and pathogenicity ...