Browsing Faculty of Basic Medical Sciences by Title
Now showing items 45-64 of 153
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EFFECTS OF CHLOROFORM EXTRACT OF CARICA PAPAYA SEED ON PREGNANCY OUTCOME AND POSTNATAL DEVELOPMENT IN RATS
(2014-01)Increasing frequency of reproductive disorders has been attributed to exposure to harmful exogenous substances during pregnancy. Studies have shown that Carica papaya seed inhibits fertility in male and oestrous cycle ... -
EFFECTS OF CHLOROQUINE, AMODIAQUINE, SULFADOXINE-PYRIMETHAMINE AND ARTESUNATE ON GASTRIC ACID SECRETION IN RATS
(2011-07)Gastric Acid Secretion (GAS) plays an important role in ulcerogenesis. Some antimalaria drugs have been shown to interfere with gastric mucosal integrity, thereby facilitating the development of gastric ulceration. ... -
EFFECTS OF CHLOROQUINE, ARTHEMETER-LUMEFANTRINE AND ARTESUNATE ON EXPERIMENTAL COLITIS IN RATS
(2014-02)Ulcerative colitis is a chronic inflammatory bowel disease characterised by inflammation, ulceration and bleeding of the colonic mucosa. The etiology is still unknown. Studies have shown that some anti-malarial drugs ... -
THE EFFECTS OF ESTROUS CYCLE AND OESTROGEN ON PLASMA AND ANTRAL GASTRIN ACTIVITY IN MAMMALS
(1975-06)Abstract The possible relationship between estrous cycle, oestrogen load and pregnancy on the one hand and antral-gastrin content, circulating plasma gastrin, parietal cell concentration and gastric acid secretion was ... -
EFFECTS OF MATERNAL SLEEP DEPRIVATION ON REPRODUCTIVE FUNCTIONS OF MALE OFFSPRINGS IN WISTAR RATS
(2017-07)Maternal Sleep Deprivation (MSD) has been reported to alter sexual performance in offsprings of rats. There is paucity of information on the critical period during gestation at which MSD affects reproductive functions. ... -
EFFECTS OF MATERNAL SLEEP DEPRIVATION ON REPRODUCTIVE FUNCTIONS OF MALE OFFSPRINGS IN WISTRAR RATS
(2017-07)Maternal Sleep Deprivation (MSD) has been reported to alter sexual performance in offsprings of rats. There is paucity of information on the critical period during gestation at which MSD affects reproductive functions. ... -
EFFECTS OF MATERNAL TREATMENT WITH DEXAMETHASONE ON MALE REPRODUCTIVE FUNCTIONS IN THE F1 AND F2 OFFSPRINGS OF WISTAR RATS
(2015-07)Maternal treatment with dexamethasone in threatening preterm delivery leads to high basal corticosterone level. This level may interfere with hormones of hypothalamic-pituitary-gonadal axis in the offspring. However, ... -
EFFECTS OF METHANOL EXTRACT OF Artocarpus altilis (BREADFRUIT) ON ATHEROGENIC INDICES AND REDOX STATUS OF CELLULAR SYSTEM OF HYPERCHOLESTEROLEMIC RATS
(2014-09)Hypercholesterolemia is a dominant risk factor for the development of cardiovascular diseases and has become a growing problem globally. Pharmacological interventions for the treatment of hypercholesterolemia involve the ... -
EFFECTS OF METHANOL EXTRATOF plukenstia conophora SEED AND 4H-PYRAN-4-ONE2,3-DIHYDRO-3,5-DIHYDROXY-6-METHYL-ON CADIUM CHLORINE-INDUCED RESPODUCTIVE TOXICITY IN WISTAR RATS
(2017-07)Infertility is a current global issue with diverse treatments. However, many infertile people especially in developing countries resort to folkloric treatment due to unyielding results from synthetic medications. ... -
EFFECTS OF Portulaca oleracea EXTRACTS ON HAEMATOLOGICAL, SERUM BIOCHEMICAL AND REPRODUCTIVE PARAMETERS IN ALBINO RATS
(2010-11)Portulaca oleracea is a herb used locally for foetal development in Edo State, Nigeria. Several studies have reported the gastrointestinal and neurological effects of the extracts, but there is a dearth of information on ... -
THE EFFECTS OF PROTEIN-CALORIE MALNUTRITION AND CHLOROQUINE THERAPY ON THE CONJUGATION OF OESTRADIOL-178 BY THE RAT LIVER
(1976-08)The conjugation of 14e-oestradiol-l7 β by rat liver homogenates was studied using a modified version of Boo and Breuer’s method (1969). This consists of incubating the homogenates with cofactors at 37°C for four hours and ... -
EFFECTS OF QUASSIA AMARA AND QUASSIN ON EPIDIDYMAL FUNCTIONS AND HORMONAL PROFILES IN RATS AND THEIR OFFSPRINGS
(2014-04)Quassia amara is a medicinal plant with antimicrobial and bitter stomachic properties. This plant and its bioactive compound quassin, have been reported to decrease sperm count, sperm motility, male fertility index and ... -
EFFECTS OF STEM BARK EXTRACT OF Alstonia boonei ON Plasmodium berghei berghei-INDUCED MALARIA IN MICE AND ON MITOCHONDRIAL PERMEABILITY TRANSITION PORE
(2013-12)Mitochondrial Membrane Permeability Transition (MMPT) pore is a target for pharmacological intervention since the release of cytochrome c upon its opening is the point of no return for apoptosis. A number of antimalarial ... -
EFFECTS OF TEMPERATURE AND EXERCISE ON THE PRODUCTION AND COMPOSITION OF SWEAT IN NIGERIANS
(1982-12)An investigation into the effects of temperature and exercise on the production and composition of sweat in Nigerians was carried out on healthy male adults. Sweat was induced in a sweat chamber under normal, exercise and ... -
EFFECTS OF THE LEAF DECOCTION OF MOMORDICA CHARANTIA (BITTER LEMON) ON MITOCHONDRIAL MEMBRANE PERMEABILITY TRANSITION PORE AND FERTILITY IN MALE ALBINO RATS
(2011-06)Certain anti-cancer agents act by inducing the intrinsic pathway of apoptosis which is mediated by the release of cytochrome C when the Mitochrondial Membrane Pemeability Transition (MMPT) pore opens. Several studies have ... -
EFFECTS OF TRIVALENT CHROMIUM ON NORMAL AND INJURED GASTROINTESTINAL TRACT IN LABORATORY RODENTS
(2016-09)Trivalent chromium (Cr3+) is an essential mineral required in quantum with reported health benefits. Chromium deficiency has been linked to symptoms associated with onset of adult diabetes and cardiovascular diseases. ... -
EFFECTS OF VITAMIN C ON CARDIAC AUTONOMIC FUNCTION, OXIDATIVE STRESS AND DYSLIPIDAEMIA IN FRUCTOSE-ALLOXAN DIABETIC RATS
(2017-06)Cardiac Autonomic Neuropathy (CAN) is characterised by cardiac autonomic dysfunction and is the principal cause of mortality in type-2 diabetes. Oxidative stress has been implicated in the aetiology of CAN, thus antioxidants ... -
EFFECTS OF VITAMIN SUPPLEMENT ON PLASMA HOMOCYSTEINE AND APOLIPOPROTEIN A₁ LEVELS IN CHILDREN WITH NEPHROTIC SYNDROME IN IBADAN, NIGERIA
(2013-04)Nephrotic Syndrome (NS), a condition characterized by proteinuria, hypoproteinaemia, and hypercholesterolaemia resulting from damage to the kidneys' glomeruli blood vessel, is a common childhood disease worldwide. Elevated ... -
ENZYME HISTOCHEMISTRY AND FUNCTIONAL DIFFERENTIATION OF THE RAT METANEPHROS
(1973-03)Since histochemistry was introduced into the study of animal tissues, many investigators have localized the site of activity of a number of enzymes in both the developing kidney the adult kidney. Moog (1944) demonstrated ... -
ERECTOGENIC AND SPERMIOLOGIC EFFECTS OF STEM BARK EXTRACTS OF Nauclea Latifolia (Smith) IN RABBITS
(2015-01)Erectile dysfunction is a sexual disorder to which both natural and synthetic remedies are being sought. Extract of Nauclea latifola (NL) has been used in folkloric medicine to ameliorate this sexual disorder; however there ...