Browsing Faculty of Basic Medical Sciences by Issue Date
Now showing items 41-60 of 153
-
THE EFFECT OF DIET AND AFLATOXIN INTAKE OF BLOOD-CLOTTING TIME AND SOME SERUM CONSTITUENTS IN NON-HUMAN PRIMATE
(1977-09)The effects of diet and aflatoxin intake on blood coagulation and serum lipid levels investigated in four different species of non-human primates namely, Carcopithecus aethiops Tantalus, Erythrocebus patas, Cercopithecus ... -
CHEMICAL AND BIOCHEMICAL STUDIES ON LEAF PROTEINS
(1978-08)Six leafy green vegetables commonly incorporated into diets by the Ibos of Anambra and Imo States of Nigeria have been used in this study. The vegetables were: Telfairia ocoidentalis, Celosia ,argeltea 'green' Celosia ... -
CARDIODYNAMIC AND HAEMODYNAMIC ASPECTS OF THE "RELAXATION RESPONSE" IN ADULT NIGERIANS
(1978-09)Experiments were carried out on 120 volunteer, unanaesthetized and intact subjects who were trained to achieve the “Relaxation Response", a behavioral stimulus situation developed as a “transcendent function'' aimed at ... -
HISTOCHEMISTRY OF RAT SMALL INTESTINE MUCOSA AFTER ORAL ADMINISTRATION SILVER NITRATE
(1979)The investigations making up the thesis were aimed towards elucidating the structural and histochemical effects of toxic doses of silver nitrate on rat small intestinal mucosa at three different sites. The studies were ... -
STUDIES IN LIPOPROTEIN LIPASES (HEPATIC AND ENTRAHEPATIC) IN PROTEIN CALORIE MALNUTRITION
(1979-02)Protein-calorie malnutrition (PCM) is a common paediatric problem in Nigeria and the two main types, kwashiorkor and marasmus show differences in serum lipid profiles. The role of lipoprotein lipase (LPL.) in lipid ... -
EFFECT OF TRADITIONAL FOOD PREPARATION TECHNIQUE ON THE NUTRITIVE VALUE OF THE FRUIT OF TRECULIA AFRICANA
(1979-09)A nutritional study was carried out with the fruit of the tree, Treculia Africana. This fruit is used as food in many parts of Africa. In this study, the whole fruit of the plant, Treculia Africana, the raw unprocessed ... -
PHARMACOLOGY STUDIES ON PRAZOSIN, A NEW ANTIHYPERTENSIVE AGENT
(1980-01)The anti-hypertensive drug prazosin brings about a blockage of alpha adrenoceptors which is thought to be different from that caused by conventional alpha adrenoceptor blocking agents. Similarly unlike conventional alpha ... -
INTERACTION OF PROSTAGLANDIN E2(PGE2) WITH NORADRENARINE AND ITS ANTAGONISTS IN THE ISOLATED MESSENTRIC ARTERY OF RAT
(1980-07)The effect of PG32, PGF2a- and PGI2, on vasoconstriction induced by different mechanisms was studied in the isolated rat mesenteric artery as described by McGregor (1965). Vasoconstriction was induced by mechanisms involving ... -
IN VITRO ABSORPTION AND METABOLISM OF SOME NATURAL ESTROGENS IN RAT INTESTINE
(1980-09)In vitro intestinal absorption and metabolism of two natural estrogens, estradiol and estrone sulphate,were studied and compared using uneverted sacs from different segments of the rat intestine. Absorption was measured ... -
PROSTAGLANDIN AND GONADOTROPIN STIMULATION OF TESTOSTERONE SECRETION IN THE RAT TESTIS
(1981-01)The response of the rat testis in vitro to gonadotropin and prostagladin El stimulation of testosterone secretion at different stages of rat development was studied. The technique employed involved the incubation of ... -
STUDIES ON THE PROBABLE EFFECT OF PROSTAGLANDINS ON CHOLINERGIC TRANSMISSION IN ISOLATED GUINEA-PIG ILEUM.
(1981-05)The effect of indomethacin, ketoprofen and sodium meclofenamate on contractions evoked by different stimuli in the guinea-pig ileum were investigated in Tyrode solution and in Krebs solution. The whole ileum preparation ... -
STUDIES ON CADMIUM TOXICITY IN RAT TISSUES
(1981-06)The presence of toxic levels of cadmium in the ecosystem has been increasing due to more and more industrial and agricultural use. Though several reports have appeared on renal damage, testicular necrosis and hepatotoxicity, ... -
ACTIONS OF SOME ANTIMALARIA AGENTS ON PLAMODIUM BERGHEI BERGHEI AND PLASMODIUM FALCIPARUM IN IN-VIVI AND IN-VITRO MODELS
(1981-07)The antimalarial actions of four drugs,Chloroquine, WR33063, Primaquine and Tetracycline have been studied on P. berqheiberghei in albino Swiss mice and P.falciparum culturein vitro. In the rodent model,the Schizontocidal ... -
STUDIES OF ZINC AND ALKALINE PHOSPHATE ISOENZYMES IN NORMAL AND TOXAEMIC PREGNANCIES IN NIGERIANS
(1982-03)ABSTRACT There is at present no information on the metabolism of zinc It during pregnancy in Nigerians. A study of zinc and a zinc melalloenzyme was therefore considered worthwhile in normal and toxaemic pregnant Nigerian ... -
EFFECTS OF TEMPERATURE AND EXERCISE ON THE PRODUCTION AND COMPOSITION OF SWEAT IN NIGERIANS
(1982-12)An investigation into the effects of temperature and exercise on the production and composition of sweat in Nigerians was carried out on healthy male adults. Sweat was induced in a sweat chamber under normal, exercise and ... -
STUDIES IN POSSIBLE BIOCHEMICAL FACTORS IN NIRIDAZONE (Anbilhar) INDUCED TOXICITY
(1983-05)Some biochemical interactions of various doses of Niridazole with tissue components have been studied. In-vivo and in-vitro studies with rats have shown that (14C) Niridazole (Anbilhar) binds covalently to tissue proteins ... -
GROUP B STREPTOCCAL INFECTIONS IN IBADAN
(1983-11)This present study on group B streptococcal (GBS) diseases was carried out between 1977 and 1982 in Ibadan, the largest indigenous Black African city, and capital of Oyo State of Nigeria, with an estimated population of ... -
A COMPARATIVE STUDY OF THE STRUCTURES OF THE RED CELL MEMBRANES AND THE CALCIUM-PUMPING ADENOSINE TRIPHOSPHATASE IN SOME MAMMALIAN SPECIES
(1984-05)Erythrocyte ghost membranes were isolated from blood samples obtained from five mammalian species, namely: (i) human (Homo sapiens), (ii) bovine (Bos taurus), (iii) porcine (Sus scrofa melitensis), (iv) ovine (Ovis aries ... -
A STUDY OF THE EFFECT OF INDUCED MALARIA (P.BERGHEI) ON THE TRANSKETOLAEE ACTIVITY AND RELATED BIOMEDICAL INDICES IN MICE AND RAT
(1984-07)Induced cerebral malaria (P. berghei) studied in mice and rats produced significant loss in the activity of the energy, transketolase which resulted in elevated thiamine pyrophosphate percentage effect (TPP%E) indicating ... -
DISPOSITION AND ANTIMALARIAL ACTIVITIES OF THE DESETHYL METABOLITES OF CHLOROQUINE
(1985-05)A fluorimetric method for the selective determination of chloroquine (chq) from biological samples following dichloromethane extraction is described. It involves the reaction of the dichloromethane extracted primary and ...