Parcourir Faculty of Basic Medical Sciences par titre
Voici les éléments 36-55 de 153
-
DISPOSITION AND ANTIMALARIAL ACTIVITIES OF THE DESETHYL METABOLITES OF CHLOROQUINE
(1985-05)A fluorimetric method for the selective determination of chloroquine (chq) from biological samples following dichloromethane extraction is described. It involves the reaction of the dichloromethane extracted primary and ... -
DISPOSITION OF AMODIAQUINE IN EXPERIMENTAL ANIMALS
(1988-12)The pharmacokinetics of amodiaquine have been examined in experimental animals (rats and rabbits) using an improved non-selective fluorimetric and more selective high performance liquid chromatographic (HPLC) methods with ... -
EFFECT OF CO-ADMINISTRATION OF ACETAMINOPHEN AND METHIONINE ON MICRONUTRIENT METABOLISM
(2013-06)Generally, altered micro-nutrient levels affect the anti-oxidant defense mechanism and impact significantly on genomic stability. Acetaminophen induces tissue damage, which is prevented by methionine. However, the influence ... -
THE EFFECT OF DIET AND AFLATOXIN INTAKE OF BLOOD-CLOTTING TIME AND SOME SERUM CONSTITUENTS IN NON-HUMAN PRIMATE
(1977-09)The effects of diet and aflatoxin intake on blood coagulation and serum lipid levels investigated in four different species of non-human primates namely, Carcopithecus aethiops Tantalus, Erythrocebus patas, Cercopithecus ... -
THE EFFECT OF DIET ON THE METABOLISM OF AFLATOXIN IN THE MAMMAL
(1968-04)The metabolic fate of aflatoxin is of interest in connection with studies related to the mode of action of hepatotoxins in the induction of liver tumors. The ability of the toxin to interact with sub-cellular particles and ... -
EFFECT OF GAMMA IRRADIATION ON ASPERGILLUS FLAVUS AND SOME OF ITS TOXIC METABOLITES
(1976-09)Studies on the resistance of aflatoxin B1, B1 + B2, G1 and G1 + G2 against gamma irradiation in the dry state and when dissolved in chloroform or methanol were carried out by means of thin-layer chromatography, fluorescence ... -
EFFECT OF TRADITIONAL FOOD PREPARATION TECHNIQUE ON THE NUTRITIVE VALUE OF THE FRUIT OF TRECULIA AFRICANA
(1979-09)A nutritional study was carried out with the fruit of the tree, Treculia Africana. This fruit is used as food in many parts of Africa. In this study, the whole fruit of the plant, Treculia Africana, the raw unprocessed ... -
EFFECTS OF 1, 4-NAPHTHOQUINONE ON MALE REPRODUCTIVE FUNCTIONS IN MICE
(2014-02)The derivative of naphthoquinone, 1, 4-naphthtoquinone, has been extensively shown to be cytotoxic, with significant antibacterial, antifungal, antiviral, insecticidal, anti-inflammatory and antipyretic properties. Many ... -
EFFECTS OF ACUTE CHRONIC ADMINISTRATION OF ETHANOL EXTRACT OF Cola nitida SCHOTT AND ENDLICHER (KOLANUT) AND CAFFEINE ON GLUCOSE METABOLISM IN RATS
(2015-12)Cola nitida is known for its high caffeine content. Caffeine administration has been shown to cause glucose intolerance and insulin resistance. However, few studies on the effect of kolanut and decaffeinated kolanut on ... -
EFFECTS OF CHLOROFORM EXTRACT OF CARICA PAPAYA SEED ON PREGNANCY OUTCOME AND POSTNATAL DEVELOPMENT IN RATS
(2014-01)Increasing frequency of reproductive disorders has been attributed to exposure to harmful exogenous substances during pregnancy. Studies have shown that Carica papaya seed inhibits fertility in male and oestrous cycle ... -
EFFECTS OF CHLOROQUINE, AMODIAQUINE, SULFADOXINE-PYRIMETHAMINE AND ARTESUNATE ON GASTRIC ACID SECRETION IN RATS
(2011-07)Gastric Acid Secretion (GAS) plays an important role in ulcerogenesis. Some antimalaria drugs have been shown to interfere with gastric mucosal integrity, thereby facilitating the development of gastric ulceration. ... -
EFFECTS OF CHLOROQUINE, ARTHEMETER-LUMEFANTRINE AND ARTESUNATE ON EXPERIMENTAL COLITIS IN RATS
(2014-02)Ulcerative colitis is a chronic inflammatory bowel disease characterised by inflammation, ulceration and bleeding of the colonic mucosa. The etiology is still unknown. Studies have shown that some anti-malarial drugs ... -
THE EFFECTS OF ESTROUS CYCLE AND OESTROGEN ON PLASMA AND ANTRAL GASTRIN ACTIVITY IN MAMMALS
(1975-06)Abstract The possible relationship between estrous cycle, oestrogen load and pregnancy on the one hand and antral-gastrin content, circulating plasma gastrin, parietal cell concentration and gastric acid secretion was ... -
EFFECTS OF MATERNAL SLEEP DEPRIVATION ON REPRODUCTIVE FUNCTIONS OF MALE OFFSPRINGS IN WISTAR RATS
(2017-07)Maternal Sleep Deprivation (MSD) has been reported to alter sexual performance in offsprings of rats. There is paucity of information on the critical period during gestation at which MSD affects reproductive functions. ... -
EFFECTS OF MATERNAL SLEEP DEPRIVATION ON REPRODUCTIVE FUNCTIONS OF MALE OFFSPRINGS IN WISTRAR RATS
(2017-07)Maternal Sleep Deprivation (MSD) has been reported to alter sexual performance in offsprings of rats. There is paucity of information on the critical period during gestation at which MSD affects reproductive functions. ... -
EFFECTS OF MATERNAL TREATMENT WITH DEXAMETHASONE ON MALE REPRODUCTIVE FUNCTIONS IN THE F1 AND F2 OFFSPRINGS OF WISTAR RATS
(2015-07)Maternal treatment with dexamethasone in threatening preterm delivery leads to high basal corticosterone level. This level may interfere with hormones of hypothalamic-pituitary-gonadal axis in the offspring. However, ... -
EFFECTS OF METHANOL EXTRACT OF Artocarpus altilis (BREADFRUIT) ON ATHEROGENIC INDICES AND REDOX STATUS OF CELLULAR SYSTEM OF HYPERCHOLESTEROLEMIC RATS
(2014-09)Hypercholesterolemia is a dominant risk factor for the development of cardiovascular diseases and has become a growing problem globally. Pharmacological interventions for the treatment of hypercholesterolemia involve the ... -
EFFECTS OF METHANOL EXTRATOF plukenstia conophora SEED AND 4H-PYRAN-4-ONE2,3-DIHYDRO-3,5-DIHYDROXY-6-METHYL-ON CADIUM CHLORINE-INDUCED RESPODUCTIVE TOXICITY IN WISTAR RATS
(2017-07)Infertility is a current global issue with diverse treatments. However, many infertile people especially in developing countries resort to folkloric treatment due to unyielding results from synthetic medications. ... -
EFFECTS OF Portulaca oleracea EXTRACTS ON HAEMATOLOGICAL, SERUM BIOCHEMICAL AND REPRODUCTIVE PARAMETERS IN ALBINO RATS
(2010-11)Portulaca oleracea is a herb used locally for foetal development in Edo State, Nigeria. Several studies have reported the gastrointestinal and neurological effects of the extracts, but there is a dearth of information on ... -
THE EFFECTS OF PROTEIN-CALORIE MALNUTRITION AND CHLOROQUINE THERAPY ON THE CONJUGATION OF OESTRADIOL-178 BY THE RAT LIVER
(1976-08)The conjugation of 14e-oestradiol-l7 β by rat liver homogenates was studied using a modified version of Boo and Breuer’s method (1969). This consists of incubating the homogenates with cofactors at 37°C for four hours and ...