Browsing Faculty of Basic Medical Sciences by Title
Now showing items 126-145 of 153
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THE RELATIONSHIP OF ENDOCRINE DISRUPTORS WITH PITUIARY GONADAL, THYROID HORMONES AND SOME RECEPTORS IN NIGERIAN WOMEN WITH BREAST CANCER
(2016-03)Endocrine Disruptors (EDs) such as lead, cadmium, arsenic, polychlorinated biphenyls (PCBs) and bisphenol-A (BPA) are associated with increased risk of Breast Cancer (BCa). Human epithelial receptor, oestrogen, progesterone ... -
REVERSAL OF SODIUM ARSENITE-INDUCED DELAY IN GASTRIC ULCER HEALING IN RATS BY KOLAVIRON, VITAMIN E AND ZINC
(2017-06)Arsenic acid is a major contaminant of various water sources used for human consumption and industrial activities in most developing countries. It has been reported to cause degenerative inflammation and oxidative damage ... -
REVERSAL OF SODIUM ARSENITE-INDUCED DELAY IN GASTRIC ULCER HEALING IN RATS BY KOLAVIRON, VITAMIN E AND ZINC
(2017-06)Arsenic acid is a major contaminant of various water sources used for human consumption and industrial activities in most developing countries. It has been reported to cause degenerative inflammation and oxidative damage ... -
RIFT VALLEY FEVER VIRUS IN NIGERIA: COMPARATIVE EXPERIMENTAL INFECTIONS OF THREE BREEDS OF INDIGENOUE SHEEP AND SERO-SURVEY OF HUMAN AND ANIMAL POPULATIONS
(1990-09)Electron microscopic examination by negative staining and antigen controlled immunodiagnosis techniques on the Zinga virus used for this study showed that it is a strain of Rift Valley fever (RVF) virus. This is based on ... -
RISK FACTORS AND EFFECTS OF ANTIMALARIAL DRUGS ON PLASMODIUM FALCIPARUM GAMETOCYTAEMIA IN NIGERIAN CHILDREN
(2007-07)Gametocytes are the sexual forms of Plasmodium species that are essential for the transmission of malaria. However, there is little information on the factors that influence their generation or carriage, a measure of ... -
THE ROLE OF 5-HYDROXYTRYPTAMINE IN THE PATHOGENESIS OF ENDONYOCARDIAL FIBROSIS
(1968-06)ENDONYOCARDIAL FIBROSIS (E.M.F) is a common heart disease in certain areas of Africa. Much knowledge has accumulated in recent years about the pathology and clinical features of this disease; but at present, its pathogenesis ... -
THE ROLE OF KUPFFER CELLS IN ETHANOL AND AFLATOXIN B₁-INDUCED p53 GENE MUTATION IN HEPATOCARCINOGENESIS
(2009-06)Kupffer cells (KC) play an important role in hepatic homeostasis, and in acute and chronic response of the liver to endotoxins. The KC also mediate the release of cykokines and reactive oxygen species (ROS) involved in ... -
THE ROLE OF OXIDATIVE STRESS IN BIOCHEMICAL, SEMINOLOGICAL AND HISTOLOGICAL CHANGES DURING ACUTE ADMINISTRATION OF ARTEMETHER
(2010)Artemether is an antimalarial drug which is effective in the treatment of multidrug resistant malaria but also induces oxidative stress in tissues. Limited information is available on role of oxidative stress in tissue ... -
THE ROLE OF RODENT AND HUMAN FACTORS IN THE PREVALENCE OF ANTIBODY TO LASSA VIRUS IN NIGERIA AND SIERRA LEONE
(1996-03)Studies were conducted on distribution of Lassa fever (LF), a viral haemorrhagic disease in humans, in Nigeria and Sierra Leone and presence of Lassa virus (LV) in rodents as it relates to human infection, using the Enzyme ... -
THE ROLE OF THE GASTROINTESTINAL TRACT IN GLUCOSE HOMEOSTASIS
(1992-06)This study was designed to investigate the role of the gastrointestinal tract in glucose handling during hyperglycaemia induced by infusion of glucose, injection of glucagon or adrenaline and during insulin -induced ... -
SELECTED GENETIC RED-CELL MARKERS AND THE EPIDEMIOLOGY OF CHLOROQUINE-ASSOCIATED PRURITUS IN NIGERIA
(1994-02)Anecdotal reports suggest that there may be a familial component to Chloroquine-associated pruritus (CAP). To test this hypothesis, the epidemiology of CAP was studied with respect to hemoglobin S (HbS) and glucose-6-phosphate ... -
SOME CHARACTERISTICS OF Bartonella henselae AN OPPORTUNISTIC PATHOGEN IN ACQUIRED IMMUNE DEFICIENCY SYNDROME
(1997-12)Cat-scratch disease (CSD) is an infectious disease, implicated as an opportunistic infection in human immunodeficiency virus (HIV) patients. So far, Bartonella henselae (Rochalimaea henselae), remains the most acceptable ... -
SOME IMMUNOLOGICAL PARAMETERS AS INDICES OF AGING IN NIGERIANS
(1994-02)This study involved 541 participants. It assessed the state of body defence mechanisms during ageing in 217 healthy Nigerians aged 6-95 years. A different group of 274 healthy subjects of ages 6 to 60 years were studied ... -
SOME IMMUNOLOGICAL REACTIONS OF TRIPANOSONA GAMBIESSE ISOLATES
(1971-02)Serological characteristics and the protective effect of humeral antibodies (serum) were examined in rabbits (a) infected with Trypanosoma gambiense, (b) immunized with killed Trypanosoma gambiense, (c) immunized with ... -
SPERM ANTIBODY AS FACTOR OF INFERTILITY IN NIGERIAN MALES
(1999-04)Sperm antibodies (SA) have been observed as a cause of infertility. The production of the SA have in some circumstances been attributed to chronic infection of the genital tract. In Nigeria, sexually transmitted diseases ... -
STUDIES IN LIPOPROTEIN LIPASES (HEPATIC AND ENTRAHEPATIC) IN PROTEIN CALORIE MALNUTRITION
(1979-02)Protein-calorie malnutrition (PCM) is a common paediatric problem in Nigeria and the two main types, kwashiorkor and marasmus show differences in serum lipid profiles. The role of lipoprotein lipase (LPL.) in lipid ... -
STUDIES IN POSSIBLE BIOCHEMICAL FACTORS IN NIRIDAZONE (Anbilhar) INDUCED TOXICITY
(1983-05)Some biochemical interactions of various doses of Niridazole with tissue components have been studied. In-vivo and in-vitro studies with rats have shown that (14C) Niridazole (Anbilhar) binds covalently to tissue proteins ... -
STUDIES OF GESTATIONAL TRAPHOBLASTIC DISEASES IN IBADAN, NIGERIA
(1975-06)Gestational Trophallactic Diseases (MTD) embrace two main lesions of which is subdivided into two-hydatidiform mole, non-invasive and invasive (chorioadenoma destruens) and choriocarcinoma. These pregnancy-associated disease ... -
STUDIES OF ZINC AND ALKALINE PHOSPHATE ISOENZYMES IN NORMAL AND TOXAEMIC PREGNANCIES IN NIGERIANS
(1982-03)ABSTRACT There is at present no information on the metabolism of zinc It during pregnancy in Nigerians. A study of zinc and a zinc melalloenzyme was therefore considered worthwhile in normal and toxaemic pregnant Nigerian ... -
STUDIES ON CADMIUM TOXICITY IN RAT TISSUES
(1981-06)The presence of toxic levels of cadmium in the ecosystem has been increasing due to more and more industrial and agricultural use. Though several reports have appeared on renal damage, testicular necrosis and hepatotoxicity, ...