Browsing Faculty of Basic Medical Sciences by Title
Now showing items 56-75 of 153
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EFFECTS OF QUASSIA AMARA AND QUASSIN ON EPIDIDYMAL FUNCTIONS AND HORMONAL PROFILES IN RATS AND THEIR OFFSPRINGS
(2014-04)Quassia amara is a medicinal plant with antimicrobial and bitter stomachic properties. This plant and its bioactive compound quassin, have been reported to decrease sperm count, sperm motility, male fertility index and ... -
EFFECTS OF STEM BARK EXTRACT OF Alstonia boonei ON Plasmodium berghei berghei-INDUCED MALARIA IN MICE AND ON MITOCHONDRIAL PERMEABILITY TRANSITION PORE
(2013-12)Mitochondrial Membrane Permeability Transition (MMPT) pore is a target for pharmacological intervention since the release of cytochrome c upon its opening is the point of no return for apoptosis. A number of antimalarial ... -
EFFECTS OF TEMPERATURE AND EXERCISE ON THE PRODUCTION AND COMPOSITION OF SWEAT IN NIGERIANS
(1982-12)An investigation into the effects of temperature and exercise on the production and composition of sweat in Nigerians was carried out on healthy male adults. Sweat was induced in a sweat chamber under normal, exercise and ... -
EFFECTS OF THE LEAF DECOCTION OF MOMORDICA CHARANTIA (BITTER LEMON) ON MITOCHONDRIAL MEMBRANE PERMEABILITY TRANSITION PORE AND FERTILITY IN MALE ALBINO RATS
(2011-06)Certain anti-cancer agents act by inducing the intrinsic pathway of apoptosis which is mediated by the release of cytochrome C when the Mitochrondial Membrane Pemeability Transition (MMPT) pore opens. Several studies have ... -
EFFECTS OF TRIVALENT CHROMIUM ON NORMAL AND INJURED GASTROINTESTINAL TRACT IN LABORATORY RODENTS
(2016-09)Trivalent chromium (Cr3+) is an essential mineral required in quantum with reported health benefits. Chromium deficiency has been linked to symptoms associated with onset of adult diabetes and cardiovascular diseases. ... -
EFFECTS OF VITAMIN C ON CARDIAC AUTONOMIC FUNCTION, OXIDATIVE STRESS AND DYSLIPIDAEMIA IN FRUCTOSE-ALLOXAN DIABETIC RATS
(2017-06)Cardiac Autonomic Neuropathy (CAN) is characterised by cardiac autonomic dysfunction and is the principal cause of mortality in type-2 diabetes. Oxidative stress has been implicated in the aetiology of CAN, thus antioxidants ... -
EFFECTS OF VITAMIN SUPPLEMENT ON PLASMA HOMOCYSTEINE AND APOLIPOPROTEIN A₁ LEVELS IN CHILDREN WITH NEPHROTIC SYNDROME IN IBADAN, NIGERIA
(2013-04)Nephrotic Syndrome (NS), a condition characterized by proteinuria, hypoproteinaemia, and hypercholesterolaemia resulting from damage to the kidneys' glomeruli blood vessel, is a common childhood disease worldwide. Elevated ... -
ENZYME HISTOCHEMISTRY AND FUNCTIONAL DIFFERENTIATION OF THE RAT METANEPHROS
(1973-03)Since histochemistry was introduced into the study of animal tissues, many investigators have localized the site of activity of a number of enzymes in both the developing kidney the adult kidney. Moog (1944) demonstrated ... -
ERECTOGENIC AND SPERMIOLOGIC EFFECTS OF STEM BARK EXTRACTS OF Nauclea Latifolia (Smith) IN RABBITS
(2015-01)Erectile dysfunction is a sexual disorder to which both natural and synthetic remedies are being sought. Extract of Nauclea latifola (NL) has been used in folkloric medicine to ameliorate this sexual disorder; however there ... -
ERYTHROCYTE Ca++, Mg++ ATPase ACTIVITY IN DIABETIC NIGERIANS
(1998-03)CA++, Mg++ -ATPase is an important enzyme in CA++ homeostasis. Its activity has been investigated in conditions like hypertension and sickle cell disease. There is no information in the literature on the activity of CA++, ... -
EVALUATION OF ANTIPSYCHOTIC EFFECTS OF METHYL JASMONATE IN MICE
(2017-01)Psychosis is a chronic neurological disorder that impairs the quality of life of the patients and remains a major health challenge worldwide. Current drugs used to manage psychosis are expensive and only provide symptomatic ... -
EVALUATION OF ANTPSYCHOTIC EFFECTS OF METHYL JASMONATE IN MICE
(2017-01)Psychosis is a chronic neurological disorder that impairs the quality of life of the patients and remains a major health challenge worldwide. Current drugs used to manage psychosis are expensive and only provide symptomatic ... -
EVALUATION OF AUTOANTIBODIES AND HEPATITIS VIRAL MARKERS IN NIGERIANS WITH LIVER DISEASES
(2011-01)Liver disease is a major public health problem. Several diagnostic and aetiologic agents of liver diseases are known, but autoantibodies to liver antigens in Nigerians with liver diseases have not been extensively studied. ... -
EVALUATION OF EPIDEMIOLOGICAL FACTORS OF MEASLES INFECTION AND SEQUENCE ANALYSIS OF A LOCAL ISOLATE OF THE VIRUS IN NIGERIA
(2000-08)Nigerian isolates of measles virus (MVNG) and its nucleotide sequence have not been compared with those of measles virus (MV) isolates from various parts of the world. This study therefore compared the neutralization ... -
EVALUATION OF EXTRACTS OF MORINDA LUCIDA AND OTHER DRUGS FOR ANTIMALARIA ACTIVITY
(1988-09)The impact of the problem of drug resistance on the capacity to provide adequate treatment for malaria is becoming more marked as more countries try to provide treatment facilities for their entire population. The need for ... -
EVALUATION OF MECHANISMS UNDERLYING ANTIDEPRESSANT-LIKE EFFECT OF METHYL JASMONATE IN MICE
(2017-11)Depression is a chronic, recurrent and severe disease that affects millions of individuals worldwide and impairs the quality of life of the patients. The clinical efficacy of existing antidepressants has been compromised ... -
EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITIES OF EXTRACTS AND FLAVONOID-RICH FRACTION FROM Ocimum gratissimum LINN.(LAMIACEAE) LEAF
(2017-08)Inflammatory responses are among causes of ill health, impaired quality of life and untimely death. Naturally occurring phenolics are sale phytochemicals that provides combinatorial multitargeted therapy in chronic ... -
EVALUATION OF THE ANTISPYCHOTIC PROPERTY OF MORIN AND ITS MECHANISMS OF ACTION IN EXPERIMENTAL MICE
(2018-06)Psychosis is a chronic neuropsychiatric disease characterised by severe behavioural perturbations. Current drugs used in the management of the disease are associated with serious side effects. Therefore, compounds with ... -
EXPERIMENTAL STUDIES ON THE ROLE OF NEURO-HUMORAL FACTORS IN PEPTIC ULCERATION
(1977-02)Using as experimental models, chronic and acute peptic ulcerations produced in rats by means of prolonged starvation and indomethacin, the role of (i) the hypothalamo-neurohypophyseal-neuro secretory system (H.N.N.S_) and ... -
A FUNCTIONAL DIFFERENTIATION OF THE GASTROINTESTINAL TRACT
(1969-04)Needham (1942) in the glossary of his book "Biochemistry and Morphogenesis" defines "functional differentiation" as the differentiation of tissues as the result of forces arising out of the functions which they are ...