Browsing Faculty of Basic Medical Sciences by Title
Now showing items 106-125 of 153
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THE MODULATION OF RAT LIVER MICROSOMAL CALCIUM ION-PUMPING ATPase BY DICOPHANE AND LOW PROTEIN INTAKE
(1992-05)The effect of the liver tumour promoter, dicophane, with those of low protein intake (LPI) in the functional expression of rat liver microsomal Ca²⁺-ATPase were compared. The effects of dicophane and LPI on the activity ... -
MOLECULAR CHARACTERIZATION OF IMPROVED CASSAVA CULTIVARS AND COMMONLY GROWN NIGERIAN LANDRACES USING SIMPLE SEQUENCE REPEAT MARKERS
(2004-02)Cassava is a starchy staple food of tropical Africa whose yield is affected by several biotic stresses. Improved cassava cultivars that are resistant to biotic stresses were developed to boost cassava production. Also, ... -
NEUROBEHAVIOURAL AND NEUROPROTECTIVE EFFECTS OF KOLAVIRON IN LABORATORY RODENTS
(2017-06)The high cost of orthodox medicines and their attendant side effects in some cases make the search for an effective and affordable alternative imperative. Kalaviron, a complex biflavanoid from Garcinia kola seeds, possesses ... -
NITROSAMINE CONTAMINATION OF SOME NIGERIAN BEVERAGES
(1976-09)N-Nitrosamines are amongst the most potent and versatile experimental carcinogens ever tested on laboratory animals. As a result, their presence and that of their precursors in food meant for human consumption is a possible ... -
NITROSAMINE CONTAMINATION OF SOME NIGERIAN INDIGENOUS BELIEVES
(1972-12)The possible role of carcinogenic nitrosamines in the aetiology of human cancer has been discussed by experts (O. Basslr, Pers. Comm.; Eisenbrand et al, 1969; Lijinakcy and Epstein, 1970). As a result of this apprehension ... -
THE NUTRIENT COMPOSITION OF SOME NIGERIAN LEAFY GREEN VEGETABLES AND PHYSIOLOGICAL AVAILABILITY OF THEIR IRON CONTENT
(1977-04)Ten leafy green vegetables, commonly incorporated into diets by peasants of the Cross River State of Nigeria, have been analyzed for their various nutrient contents. The vegetables were Abelmoschus esculentus, Corohorus ... -
THE NUTRIENT COMPOSITION OF SOME NIGERIAN LEAFY GREEN VEGETABLES AND PHYSIOLOGICAL AVAILABILITY OF THEIR IRON CONTENT
(1973-02)ABSTRACT In order to investigate the potential usefulness of local foodstuffs in Nigeria, a comprehensive survey of the various nutrients in 10 local vegetables was carried out. The survey covers: total nitrogen and total ... -
NUTRITIONAL CHANGES IN SOME NIGERIAN FOODS DURING DIETARY PREPARATION AND THEIR EFFECTS ON THE MAMMALIAN BODY
(1967-06)Starting with a comprehensive review of the research already done in the related field of nutrition, the chemical composition of 20 Nigerian food materials which are used in the preparation of six common local diets has ... -
ORUNGO ( UgMP 359) VIRUS: A HITHERTO UNDESCRIBED VIRUS, BIOCHEMICAL, BIOPHYSICAL AND EPIDEMIOLOGICAL STUDIES
(1976-07-14)Orungo virus, a hitherto undescribed virus, first isoated from a pool of Anopheles mosquitoes caught off human bait in Uganda was studied by biochemical, biophysical and sero- epidemiological methods. These studies were ... -
PHARMACOLOGY STUDIES ON PRAZOSIN, A NEW ANTIHYPERTENSIVE AGENT
(1980-01)The anti-hypertensive drug prazosin brings about a blockage of alpha adrenoceptors which is thought to be different from that caused by conventional alpha adrenoceptor blocking agents. Similarly unlike conventional alpha ... -
PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON SOME CONSTITUENTS OF VERNONIA AMYGDALINA
(1995-11)Some saponins and flavonoids occuring in the leaves of Vernonia amygdalina (Compositae) and the biological response they elicited were investigated. C18 fractionation of a 169 g methanolic extract of the leaves using 30-70% ... -
PRESENCE OF N-NITROSAMINES AND RELATED COMPOUNDS IN HUMAN AND ANIMAL FOODS
(1991-02)The nitrosamine, nitrate, ntirite and amine contents of some indigenous vegetables, soup condiments, cereals, food staples and forages of tropical interest were investigated. Also examined were the nitrosation of these ... -
PRODUCTION OF MONOCLONAL AND POLYCLONAL ANTIBODIES FOR THE DIAGNOSIS OF BANANA STREAK VIRUS, GENUS BADNAVIRUS
(2001-07)BSV was isolated and purified from infected leaves of IITA plantain hybrids (TMPx) by Methods A & B. Method A involved the use of sucrose cushion and caesium gradient during ultracentrifugation, while method B involved the ... -
PROSTAGLANDIN AND GONADOTROPIN STIMULATION OF TESTOSTERONE SECRETION IN THE RAT TESTIS
(1981-01)The response of the rat testis in vitro to gonadotropin and prostagladin El stimulation of testosterone secretion at different stages of rat development was studied. The technique employed involved the incubation of ... -
PROTECTIVE EFFECT OF Pterocarpus mildbraedii HARMS EXTRACT ON PROPANIL-INDUCED HEPATOTOXICITY AND ALTERATIONS IN APOPTOTIC RELATED PROTEINS IN WISTAR RATS
(2017-05)One of the probable causes of liver diseases is exposure to environmental chemicals. Agrochemicals containing propanil are known to induce hepatic toxicity. Pterocarpus mildbraedii leaf is used in traditional medicine to ... -
PROTECTIVE EFFECTS OF KOLAVIRON AND QUERCETIN ON ATRAZINE-INDUCED NEURONAL AND TESTICULAR DAMAGE IN CELL LINES AND RATS
(2012-10)Neurodegenerative diseases and decline in male fertility are reported to be associated with exposure to environmental chemicals. Many agrochemicals including atrazine are known to induce reproductive and neuronal toxicity. ... -
PROTECTIVE EFFECTS OF METHANOL EXTRACT OF Allium cepa ON CYANIDE-INDUCED TOXICITY IN WISTAR RATS
(2015-04)Cyanide inhibits cellular cytochrome C oxidase, promotes reactive oxygen species production and causes organ damage. The possible ameliorative effects of Methanol Extract of the Bulb of Allium cepa (MEAC) on cyanide intake ... -
PROTECTIVE EFFECTS OF METHANOL EXTRACT OF Chasmanthera dependens HOCHST STEMON ACIDIFIED ETHANOL-AND INDOMETHACIN-INDUCED GASTRIC ULCER AND APOPTOSIS IN MALE WISTAR RATS
(2015)Gastric ulceration is a common clinical problem which may results from incessant use of drugs. Chasmanthera dependens possesses analgesic effects in experimental rats and anecdotal report exit on its gastric ulcerogenic ... -
PROTECTIVE EFFECTS OF QUERCETIN AND RUTIN ON SULFASALAZINE-INDUCED TESTICULAR TOXICITY AND APOPTOSIS IN MALE WISTAR RATS
(2015-08)Sulfasalazine is used as a therapy for inflammatory bowel diseases. High doses may be associated with male infertility; reversible only on drug withdrawal. Sulfasalazine metabolism generates oxidative stress as a mechanism ... -
PROTECTIVE ROLE OF PROTOCATECHUIC ACID IN NEVIRAPINE-INDUCED HEPATOTOXICITY AND APOPTOSIS IN MALE WISTER RATS
(2015-08)Nevirapine is a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) used in HIV-I treatment. Although efficacious, it produces toxic responses such as hepatotoxicity which is characterised by generation of free radicals. ...